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A Phase 2 trial of MTX-463 in idiopathic pulmonary fibrosis expected in 1H 2025.
January 10, 2025
By: Kristin Brooks
Managing Editor, Contract Pharma
Mediar Therapeutics, Inc., a clinical stage biotechnology company developing first-in-class therapies designed to halt fibrosis progression, signed a global licensing agreement with Eli Lilly and Co. to advance MTX-463 into a Phase 2 clinical trial for idiopathic pulmonary fibrosis (IPF). MTX-463 is a first-in-class human IgG1 antibody designed to neutralize WISP1-mediated fibrotic signaling in several debilitating diseases. The Phase 1 study showed MTX-463 to be well-tolerated and engaged WI...
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